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Research Assistant (Gilbertson Group) (Fixed Term)


We are seeking a motivated and skilled in vivo Research Assistant to join the group of Professor Richard Gilbertson at the Cancer Research UK Cambridge Institute. The Gilbertson lab is dedicated to understanding the origins and progression of paediatric brain tumours and developing new therapeutic strategies. The lab combines genetic engineering, molecular biology, and translational research to investigate the cellular and molecular mechanisms driving tumour development.

In this role, you will support a team of scientists using genetically engineered mouse models (GEMMs) and transplantable tumour models (e.g., orthotopic, patient-derived xenografts) to study cancer biology and therapeutic response. You will play a key role in helping establish, monitor and analyse in vivo models, working collaboratively with postdoctoral researchers, students, and other research staff in the group.

Key responsibilities will include:

  • Performing successful engraftment of patient biopsies or cell lines to generate xenograft or orthotopic tumour models
  • Supporting preclinical treatment studies involving standard-of-care or experimental agents
  • Applying in vivo imaging techniques (e.g., bioluminescence imaging) to monitor tumour development and treatment effects
  • Performing minor surgical procedures and sample collection as part of study protocols
  • Conducting detailed necropsies and tissue dissections for downstream molecular analyses
  • Maintaining accurate and organised records of animal studies and ensure data is captured in lab databases
  • Complying with all regulatory requirements including Home Office licences, local AWERB oversight, and institutional biosafety and welfare protocols
  • The successful candidate will hold a B.Sc. or M.Sc. in a relevant discipline (e.g., Biomedical Sciences, Oncology, or Neuroscience), and a Home Office Personal Licence (Modules A, B and C or equivalent). They should have demonstrable experience in a range of in vivo techniques, including the establishment and monitoring of tumour models in small animals, and experience in colony management. Proficiency in performing animal procedures and related experimental techniques is essential. In addition to in vivo responsibilities, the role may also involve supporting laboratory-based experiments such as tissue processing for multi-omic studies, Western blotting, cell culture, and immunohistochemistry. The ideal candidate will be proactive, adaptable, and capable of working effectively under pressure, with excellent communication skills and a strong focus on teamwork and accurate data recording. This position offers the opportunity to contribute directly to impactful cancer research in a dynamic and supportive team.

    For more information on the suitability of your research experience for the role, please email cbtce@cancer.cam.ac.uk / erica.nathan@cruk.cam.ac.uk

    Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

    Fixed-term: The funds for this post are available for 2 years in the first instance.

    Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check.

    Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

    If you have any queries regarding the application process, please contact: mailbox-hr@cruk.cam.ac.uk.

    Please quote reference SW46580 on your application and in any correspondence about this vacancy.

    The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

    The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

    Further information

    Apply online